38 results
Plasmacytomas and Plasma-Cell Leukemia - Physical examination revealed multiple exophytic subcutaneous lesions involving the arms and
peripheral-blood smear ... revealed 25% plasma cells ... PlasmaCell #Leukemia #Smear ... #NEJM
Prolymphocytes

In our case, the patient has T-prolymphocytic leukemia (T-PLL) not Acute Myeloid Leukemia (AML).  🔬Tumor
Prolymphocytes In our case ... 🔬Tumor cells are ... 𝐩𝐫𝐨𝐥𝐲𝐦𝐩𝐡𝐨𝐜𝐲𝐭𝐞𝐬: small to medium ... size lymphoid cells ... Prolymphocytes #Smear
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood Smear ... anemia Sickled red cells ... disease Bite cells ... Alcohol abuse, Heavy metal ... Peripheral #Blood #Smear
Spur-Cell Anemia- A 31-year-old man with a history of cirrhosis, recurrent hepatic encephalopathy, and anemia presented
peripheral-blood smear ... acanthocytes (or spur cells ... Spur cells acquire ... #NEJM #clinical ... peripheral #blood #smear
Hemolytic Anemia - Differential Diagnosis Algorithm
Hereditary:
 • Peripheral blood smear + DAT + further History
 •
Peripheral blood smear ... History • Bite cells ... Deficiency • Sickle cells ... Diagnosis #Algorithm #causes
Schistocytes can assume a shape resembling natural or man-made objects such as arrowheads, fish, collar buttons,
In this case, arrows ... point to helmet cells ... cell, 2 blister cells ... acanthocyte), and 2 burr cells ... BloodSmear #Blood #Smear
Mastoiditis: Pathogenesis and clinical findings

Acute or Chronic Otitis Media -> 
Stage 1: Hyperemeia of the mastoid
Chronic Otitis Media ... the mastoid air cells ... Inferior through medial ... under SCM • Medially ... hearing loss, nausea
Nucleated red blood cells, aka normoblasts or erythroblasts, were released prematurely from the bone marrow in
Nucleated red blood cells ... other nucleated cells ... fetus/newborn the causes ... BloodSmear #Blood #Smear
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
incidentally during medical ... Eosinophilia, 500-1,500 cells ... Hypereosinophilia, >1,500 cells ... for secondary causes ... eosinophilia (common causes
Spherocytes - The arrow points to one of many spherocytes in this photo. The cells have
The cells have assumed ... This smear was from ...

Causes of spherocyte ... BloodSmear #Blood #Smear