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diagnosis differential causes hyperkalemia nephrology cardiology classification hypokalemia pharmacology antiarrhythmics digoxin high phases vaughan williams
Causes of Hypokalemia - Differential Diagnosis Algorithm Increased Loss - Increased GI Loss - Increased Urinary
Differential Diagnosis Algorithm ... cells: Insulin, Beta-Agonist ... Differential #Diagnosis #Algorithm ... #causes #potassium ... #low #pathophysiology
Antiarrhythmics - Vaughan Williams Classification: CLASS 1 - Sodium Channel Blockers: • MOA: Block fast Na+ channels
2 - Beta Blockers ... of phase 4 to slow ... 3 - Potassium Channel ... alpha & beta adrenergic ... #pathophysiology
Causes of Hyperkalemia - Reduced Excretion - Differential Diagnosis Algorithm Reduced flow through distal nephron - TTKG
Differential Diagnosis Algorithm ... Aldosterone • ENaC blockers ... nephropathy • Beta ... #Hyperkalemia #IntercellularShift ... Differential #Diagnosis #Algorithm
Hypokalemia - Differential Diagnosis Algorithm Transcellular Shift: • Alkalosis • ↑ beta-2 adrenergic simulation • Erythropoiesis
Differential Diagnosis Algorithm ... Alkalosis • ↑ beta ... vomiting) • Low ... #nephrology #low ... #potassium
Antiarrhythmics Pharmacology Summary Cardiac Conduction Phases: Phase 0 - Ventricular Depolarization: • Na+ channels open leading to a
open leading to slow ... 2 - Beta Blockers ... 3 - Potassium Channel ... alpha & beta adrenergic ... #pathophysiology
The Diagnostic Approach to Hyperkalemia Drugs - Amiloride - Spironolactone - Triamterene - Trimethoprim - Pentamidine -
inhibitors Other causes ... Ketoconazole Low ... - NSAlDs - Beta-Blockers ... #Hyperkalemia #Algorithm ... #differential #causes
Digoxin Pharmacology and Pathophysiology 1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Pharmacology and Pathophysiology ... - When digoxin blocks ... intracellular calcium causes ... Since digoxin blocks ... hypokalemia (or low
Causes of Hyperkalemia - Intercellular Shift - Differential Diagnosis Algorithm Transcellular Shift - Appropriate renal excretion (GFR,
Differential Diagnosis Algorithm ... , TTKG, distal flow ... Resistance • Beta ... #Hyperkalemia #IntercellularShift ... Differential #Diagnosis #Algorithm
Causes of Hyperkalemia l. Pseudohyperkalemia A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis B.
Causes of Hyperkalemia ... Beta-Adrenergic ... inhibitors, ß-blockers ... Drug-associated: heparin, low-molecular-weight ... Diagnosis #High #Potassium
Pragmatic diagnostic algorithm for hypokalemia. ***Typical presentations: • Vomiting: urine Na/Cl > 1.6, low urine
Pragmatic diagnostic algorithm ... urine Na/Cl > 1.6, low ... correcting serum potassium ... angiotensin receptor blockers ... continued in most cases
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