16 results
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
inhibition (NSAIDs, Beta-Blockers ... #hyperkalemia #differential ... #diagnosis #pathophysiology ... #pharmacology # ... potassium #medications
Pharmaceutical Management of Hyperthyroidism / Thyroid Storm
Beta-Blockers 
• Decreases sympathetic hyperactivity 
• Partially blocks peripheral conversion
Thyroid Storm Beta-Blockers ... peripheral conversion ... • Decreases conversion ... ThyroidStorm #Management #Pharmacology ... #Medications #Drugs
Antiarrhythmic Medications - Vaughan Williams Classification - Summary Table
Class I agents - Sodium Channel Blockers⠀
Class II
Antiarrhythmic Medications ... this class are beta ... III agents - Potassium ... Antiarrhythmic #Medications ... Summary #Table #pharmacology
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
that Impair Renal Potassium ... Release: NSAIDs, Beta-Blockers ... #Hyperkalemia #Pathophysiology ... #Pharmacology # ... Impaired #Potassium
Beta-Blockers in Cirrhosis
 • Pathophysiology
 • Indications:  Prevention of decompensation, Prevention of first variceal bleeding,
Beta-Blockers in ... Cirrhosis • Pathophysiology ... • Indications: ... hepatology #management #pharmacology ... #indications #dosing
Potassium Channel Blockers - Medications
1. Cardiovascular Drugs
2. Psychiatric drugs
3. Other drugs
4. Synthetic opioids: Levomethadyl 
5. Opium
Potassium Channel ... Blockers - Medications ... ChannelBlockers #Medications ... #Differential # ... Diagnosis #Pharmacology
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Hypokalemia - Differential ... Alkalosis • ↑ beta ... Thyrotoxicosis Medications ... Diagnosis #Algorithm #nephrology ... #low #potassium
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... • Recent IV potassium ... • Beta blockers ... Medications 2. ... #high #nephrology
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
duration CLASS 2 - Beta ... repolarization CLASS 3 - Potassium ... alpha & beta adrenergic ... Vaughan #Williams #Pharmacology ... Classification #Classes #pathophysiology
Common sodium channel blockers which cause QRS widening.

Anticonvulsants: 
 - Carbamazepine 
Antidysrhythmics:  
 - Group
sodium channel blockers ... - Amantadine Beta ... widening #ECG #EKG #Pharmacology ... #Medications #Toxicology ... #Diagnosis #Differential