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diagnosis differential causes hyperkalemia potassium antiarrhythmics cardiology hypokalemia pharmacology acg achalasia disorders gastroenterology guidelines hematology hepatology hepatorenal hrs lymphomas lymphoproliferative
Antiarrhythmics - Vaughan Williams Classification: CLASS 1 - Sodium Channel Blockers: • MOA: Block fast Na+ channels
Vaughan Williams Classification ... 2 - Beta Blockers ... alpha & beta adrenergic ... #Pharmacology #Classification ... #Classes #pathophysiology
Causes of Hyperkalemia - Reduced Excretion - Differential Diagnosis Algorithm Reduced flow through distal nephron - TTKG
Differential Diagnosis Algorithm ... • ENaC blockers ... nephropathy • Beta ... #Hyperkalemia #IntercellularShift ... #Nephrology #Differential
Antiarrhythmics Pharmacology Summary Cardiac Conduction Phases: Phase 0 - Ventricular Depolarization: • Na+ channels open leading to a
Vaughan Williams Classification ... 2 - Beta Blockers ... alpha & beta adrenergic ... #Pharmacology #Classification ... #Classes #pathophysiology
The Diagnostic Approach to Hyperkalemia Drugs - Amiloride - Spironolactone - Triamterene - Trimethoprim - Pentamidine -
inhibitors Other causes ... transplant - SLE High ... - NSAlDs - Beta-Blockers ... #Hyperkalemia #Algorithm ... #differential #causes
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
phlebotomy High ... potassium • Beta ... cell membrane - Beta ... #potassium #high ... #nephrology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
phlebotomy High ... potassium • Beta ... cell membrane - Beta ... #potassium #high ... #nephrology
Causes of Hyperkalemia - Intercellular Shift - Differential Diagnosis Algorithm Transcellular Shift - Appropriate renal excretion (GFR,
Differential Diagnosis Algorithm ... Resistance • Beta ... #Hyperkalemia #IntercellularShift ... #Nephrology #Differential ... #Diagnosis #Algorithm
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... are present • Classic ... age range • High ... Lymphoproliferative #Disorders #Classification ... #pathophysiology
Hepatorenal Syndrome (HRS) Definition: • Functional, potentially reversible kidney impairment. • Occurs in advanced liver disease: cirrhosis, severe alcoholic
Pathophysiology: ... Exclude other AKI causes ... Classification: ... Prognosis: • High ... Syndrome #Hepatology #Nephrology
Causes of Hypokalemia - Differential Diagnosis Algorithm Decreased intake (rare cause in isolation) GI loss - Urine loss
Differential Diagnosis Algorithm ... • Insulin • Beta ... #Hypokalemia #Nephrology ... Differential #Diagnosis #Algorithm ... #Causes
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