28 results
Glucagon: Bypassing β-Blockade

Glucagon pathophysiology and clinical applications in anaphylaxis and beta-blocker overdose

#Toxicology #Pharmacology #Pathophysiology #Glucagon #BetaBlocker
β-Blockade Glucagon pathophysiology ... anaphylaxis and beta-blocker ... overdose #Toxicology ... #Pharmacology #Pathophysiology ... #BetaBlockade #Overdose
Management of acute beta blocker/calcium channel blocker overdose

#Management #Toxicology #BetaBlocker #CCB #CalciumChannelBlocker #Overdose #Toxicity #Algorithm
Management of acute beta ... blocker/calcium ... channel blocker ... overdose #Management ... #Toxicity #Algorithm
Beta-Blocker Overdose/toxicity:

•	Bradycardia & hypotension (most common).
•	Myocardial depression & cardiogenic shock (severe overdoses). 
•	Ventricular dysrhythmias (Common with
Beta-Blocker Overdose ... shock (severe overdoses ... labetalol) #Beta-Blocker ... #Overdose #toxicity
Bradycardia Diagnostic and Management Algorithm

CONSIDER ETIOLOGY (not inclusive): 
 - STRUCTURAL: sick sinus, AV block, ischemia,
and Management Algorithm ... sick sinus, AV block ... Hypothyroidism - TOX: beta-blockers ... TREATMENT - Drugs (beta-blockers ... #Bradycardia #Algorithm
Intravenous Lipid Emulsion (ILE) Therapy

ILE is a treatment for severe toxicity from local anesthetics. In addition,
diphenhydramine) • beta ... blockers • bupropion ... calcium channel blockers ... #Pharmacology #Overdose
Atrial Fibrillation RVR - Medications
Diltiazem
 • Preferred in patients with chronic lung such as Asthma and
• Long-term β-blocker ... thus starting a β-blocker ... to 6-8 hours to work ... rate control when beta-blockers ... conjunction with beta-blockers
Beta-Blockers in Cirrhosis
 • Pathophysiology
 • Indications:  Prevention of decompensation, Prevention of first variceal bleeding,
Beta-Blockers in ... Cirrhosis • Pathophysiology
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
Sodium Channel Blockers ... : • MOA: Block ... duration CLASS 2 - Beta ... alpha & beta adrenergic ... Classification #Classes #pathophysiology
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
inhibition (NSAIDs, Beta-Blockers ... Angiotensin II Receptor Blockers ... Sodium-channel blockers ... differential #diagnosis #pathophysiology
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
Release: NSAIDs, Beta-Blockers ... #Hyperkalemia #Pathophysiology