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hematology algorithm anemia management oncology classification workup hemolysis radiology syndrome thrombocytosis arthritis lad lymphadenopathy mri neurology neutropenia thrombocytopenia approach blood
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
- Differential ... Diagnosis Algorithm ... / unconjugated bilirubin ... Hypersplenism, Infection ... #hematology
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Hemolysis - Diagnostic ... Algorithm and Causes ... Increased Serum bilirubin ... #Algorithm #Differential ... #Hematology #Diagnosis
Causes of Hemolytic Anemia - Differential Diagnosis Inherited • Membrane • Internal - Hemoglobin
Causes of Hemolytic ... Anemia - Differential ... Internal - Infectious ... #Diagnosis #Causes ... #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... Extravascular #Causes ... #differential # ... diagnosis #hematology
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Anemia 1) DIAGNOSE ... haptoglobin ↑ indirect bilirubin ... • Blood smear: Differential ... 2) LOOK FOR a cause ... management #treatment #rheumatology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... - Differential ... Diagnosis Algorithm ... circulation - Infections ... #Causes #Hematology
Thrombocytosis - Differential Diagnosis Platelet Count > 450 Reactive: • Anemia/blood loss (Fe deficiency) • Infection/Sepsis • Non-infectious
Thrombocytosis - Differential ... Diagnosis Platelet ... deficiency) • Infection ... #Diagnosis #causes ... #Platelets #hematology
Classification of Jaundice Unconjugated hyperbilirubinemia (predominantly indirect bilirubin) • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
production (eg, hemolytic ... anemias, hemolytic ... eg, spirochetal infections ... Classification #diagnosis ... #unconjugated #differential
Causes of Leukocytosis and Leukopenia - Differential Diagnosis • Eosinophilia (AEC > 500, hypereosinophilia > 1500):
Causes of Leukocytosis ... and Leukopenia - Differential ... Diagnosis • Eosinophilia ... #Diagnosis #causes ... #hematology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... drug induced • Infections ... #Diagnosis #causes ... classification #hematology
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