26 results
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
Diagnosis and Management ... Total/indirect bilirubin ... Differential #Diagnosis #Management ... #Algorithm #hematology
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
haptoglobin ↑ indirect bilirubin ... Anemia #diagnosis #management ... #treatment #rheumatology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
arthritis, Skin rash ... hepatomegaly, hepatitis ... Disease #diagnosis #management ... #treatment #rheumatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Check Acute viral hepatitis ... Check Acute viral hepatitis ... week • Direct bilirubin ... disease: > 2 • NASH ... #differential #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
week • Direct bilirubin ... disease: > 2 • NASH ... Chronic viral hepatitis ... Elevation: • Bilirubin ... diagnosis #algorithm #hepatology
Treatment of Non-hepatitis C virus Cryoglobulinemia Vasculitis - French Vasculitis Study Group

MONOCLONAL CRYOGLOBULINEMIA (TYPE 1) 
IgM
Treatment of Non-hepatitis ... Cryoglobulinemia #Vasculitis #Management ... #Rheumatology #
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... injury (INR > 2, bilirubin ... liver failure #HepatitisB ... #Indications #management ... #hepatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Petechial or purpuric rash ... ↑ AST ↑ ALT ↑ bilirubin ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Diagnosis and Management ... Manifestations: Malar rash ... Usual therapeutic management ... Erythematosus #Diagnosis #Management ... #Summary #rheumatology
Kawasaki Disease (KD) - Diagnosis and Management Summary

Kawasaki Disease (KD) is the most common vasculitis of
Diagnosis and Management ... Conjunctivitis, Mucositis, Rash ... Polymorphous rash ... lymphadenopathy Management ... KD #vasculitis #rheumatology