33 results
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
normal - Ischemic Hepatitis ... - Acute Viral Hepatitis ... , Toxic Hepatitis ... normal - Hemolysis, NASH ... Liver #Injury #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Check Acute viral hepatitis ... Check Acute viral hepatitis ... week • Direct bilirubin ... disease: > 2 • NASH ... #differential #Hepatology
DRESS Syndrome vs SJS/TEN
DRESS
 • Latency: 2-8 weeks
 • Rash: Morbilliform
 • Mucosal involvement: 50% have
: 2-8 weeks • Rash ... leukocytosis • Hepatitis ... : 4-28 days • Rash ... Lymphopenia • Hepatitis ... comparison #table #dermatology
Clinical diagnosis of Alcoholic Hepatitis (AH)
 • Onset of jaundice within prior 8 weeks
 • Ongoing
diagnosis of Alcoholic Hepatitis ... • Serum total bilirubin ... Possible ischemic hepatitis ... diagnosis #Alcoholic #Hepatitis ... #AH #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
week • Direct bilirubin ... disease: > 2 • NASH ... Chronic viral hepatitis ... Elevation: • Bilirubin ... diagnosis #algorithm #hepatology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
fold elevation, Bilirubin ... fold elevation, Bilirubin ... but variable ++, Bilirubin ... Disease #Pregnancy #hepatology ... #obstetrics #hepatitis
Clinical Diagnosis of Autoimmune Hepatitis
 - Onset of jaundice within prior 8 weeks
 - Ongoing consumption
of Autoimmune Hepatitis ... - Serum total bilirubin ... Possible ischemic hepatitis ... #Autoimmune #Hepatitis ... #Diagnosis #Hepatology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial Rash ... : • Palpable Rash ... • Non-Palpable Rash ... • Serology for hepatitis ... Algorithm #Causes #dermatology
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... injury (INR > 2, bilirubin ... liver failure #HepatitisB ... Indications #management #hepatology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
arthritis, Skin rash ... hepatomegaly, hepatitis ... management #treatment #rheumatology