15 results
differential algorithm abnormal coagulation management prolonged liver pt workup activation biliary bleeding bruising chemistry cholangitis cirrhosis congenital dic disseminated enlarged
How to Evaluate an Abnormal APTT Step 1: Is the PT or APTT Artifactually Prolonged? Step 2: Is
K Antagonists, Heparin ... Prolonging the PT or APTT ... to identify the cause ... #prolonged #diagnosis ... #hematology #evaluation
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm Suspected TMA: Unexplained thrombocytopenia + MAHA
- Differential Diagnosis ... hemoglobin/hemosiderin, Hepatic ... Total/indirect bilirubin ... hemosiderin • PT/aPTT ... Management #Algorithm #hematology
Jaundice - Differential Diagnosis Algorithm Pre-Hepatic - Unconjugated Hyperbilirubinemia Increased Production • Hemolysis • Ineffective Erythropoiesis • Hematoma Decreased
- Differential Diagnosis ... Algorithm Pre-Hepatic ... #Differential #Diagnosis ... #Algorithm #Causes ... #Hepatology #bilirubinemia
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... (e.g. heparin contamination ... thrombin inhibitors, heparin ... #diagnosis #differential ... #hematology #coagulation
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
- Differential Diagnosis ... function: INR, bilirubin ... : • Cardiac causes ... #Differential #Diagnosis ... #causes #hepatology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... unfractionated heparin ... e.g. heparin ... #diagnosis #differential ... #hematology #coagulation
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
- Differential Diagnosis ... Hepatic, Portal, ... Myeloproliferative disorders (eg ... #Differential #Diagnosis ... #Hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Treat primary cause ... INR < 2.3 - APTT ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Inherited Non-hemolytic Disorders of Hyperbilirubinemia == Disorders of Conjugation == Gilbert Syndrome: • 5-10% of the population
birth with serum bilirubin ... associated with bilirubin ... and stress may cause ... • Defect in hepatic ... #hepatology #diagnosis
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Chemistries - Interpretation ... replaced by non-hepatic ... liver #chemistry #diagnosis ... #differential #Hepatology ... #LFTs #RValue #interpretation
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