9 results
Pharmacology of diuretics

Acetazolamide, Loop diuretics, Thiazide‐like diuretics, MRA, Amiloride

Site of Action, Maximum Dose, Half-Life, Onset, Bioavailability,
Pharmacology of diuretics ... Half-Life, Onset, Bioavailability ... , Absorption # ... #Comparison #Table ... Loop #Thiazide #CHF
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
Nephron and their Functions ... organic acids and bases ... acid and most diuretics ... #Pathophysiology ... #Tubules #Table
Iron Deficiency in Heart Failure
Pathophysiology:
Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Heart Failure Pathophysiology ... → Inflammation causes ... decreased iron absorption ... with TSAT <20% (functional ... iron #deficiency #CHF
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Differential Diagnosis Algorithm ... RENAL LOSS: - Diuresis ... transport, renal function ... Gastrointestinal function ... #Pathophysiology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Weakness, cramping, nausea ... Na delivery): CHF ... Ureterojejunostomy (reabsorption ... only if no clear cause ... Elimination (see Table
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Urinary Chloride Algorithm ... loop or thiazide diuretics ... Vomiting/nasogastric suction ... pressure: Active diuretic ... the indicated causes
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
blood donor • Pathophysiology ... without other cause ... : Age>60, CKD, CHF ... : Supportive + diuresis ... diagnosis #comparison #table
Thiamine Deficiency - Differential Diagnosis Framework and Clinical Manifestations

Causes of Thiamine Deficiency:
 • Poor intake:
	- Diets
Manifestations Causes ... surgery • Poor absorption ... gravidarum - Diuretic ... triggers Right HF ... beriberi #nutrition #pathophysiology
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
excreted using diuretics ... the determined cause ... #differential #algorithm ... cardiology #treatment #table ... #heartfailure #chf