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management pharmacology diagnosis diuretics table treatment alkalosis differential hyponatremia metabolic siadh thiazide algorithm binders cardiology causes chf chloride classes conversion
Pharmacology of diuretics Acetazolamide, Loop diuretics, Thiazide‐like diuretics, MRA, Amiloride Site of Action, Maximum Dose, Half-Life, Onset, Bioavailability,
Acetazolamide, Loop ... Half-Life, Onset, Bioavailability ... , Absorption # ... #Pharmacology #Comparison ... HalfLife #Dosing #Loop
NSAIDS and their effects on the Kidney - Pathophysiology Arachidonic Acid metabolites into alternative pathways that modify
NSAIDS and their effects ... in Proximal, loop ... • Increase H2O absorption ... KidneyDisease #nephrology ... #Effects #pathophysiology
Diuretic Electrolyte Excretion Effects Diuresis, Na+, K+, Mg2+, Ca2+, Cl-, HCO3-, Uric Acid - Thiazide Type
Electrolyte Excretion Effects ... Acid - Thiazide Type ... - Loop - Aldosterone ... #electrolytes #effects ... #pharmacology #comparison
Diuretics - Pharmacology Thiazides diuretics: • Inhibit Na+ Cl- cotransporter in distal tubule • Chlorothiazide, Chlorthalidone, Indapamide,
Metolazone Loop ... diuretic as no effect ... on sodium reabsorption ... #Pharmacology #nephrology ... #conversion #loop
Causes of Metabolic Alkalosis: Differential Diagnosis ECF volume contracted: urine chloride concentration <20 meq/L • Gastric alkalosis:
• Thiazide or loop ... tubule diuretic effect ... syndrome (11-ß HSD type ... in loop of Henle ... Diagnosis #Causes #nephrology
Phosphate Binders - Pros and Cons Calcium carbonate (TumsTM) - Most inexpensive, antacid properties useful for
less GI calcium absorption ... anti-inflammatory effect ... edgarvlermamd - Nephrology ... Binders #Table #Comparison ... #Pharmacology #Nephrology
Management of SIADH Treat underlying cause: • Causes can include pain, primary lung pathology, post-operative phenomenon, medications,
passive sodium reabsorption ... ascending limb of the loop ... Has many side effects ... #hyponatremia #nephrology
SIADH Treatment Options 1. Treat underlying cause of SIADH: Pain, Primary lung pathology, Post-operative phenomenon, Medications, Basically
passive sodium reabsorption ... ascending limb of the loop ... • Major side effects ... #hyponatremia #nephrology
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
Remote use of loop ... mineralocorticoid-like effect ... acidosis-induced decreased reabsorption ... urine #Algorithm #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Aldosterone, RTA Type ... Ureterojejunostomy (reabsorption ... Diuretics (IV loop ... acetazolamide) - IV loop ... Treatment #potassium #nephrology
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