10 results
Tweetorial - Why do we use Vitamin C (ascorbic acid) to promote iron absorption?

By Dr. Tony
acid) to promote iron ... absorption? ... #VitaminC #AscorbicAcid ... #Iron #Absorption ... #Pathophysiology
Iron Deficiency in Heart Failure
Pathophysiology:
Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Heart Failure Pathophysiology ... → Inflammation causes ... absorption and ... improvement in symptoms ... endpoint of all-cause
Causes of Iron Deficiency - Differential Diagnosis Algorithm
 • Blood loss: GI (cancer, ulcer, IBD), GU
Causes of Iron Deficiency ... Differential Diagnosis Algorithm ... loss of sites of absorption ... Differential #Diagnosis #Causes ... #Fe #algorithm
Pseudogout: pathogenesis and clinical findings
 - Idiopathic (vast majority of cases) -> Mechanism unknown
 - Familial
vast majority of cases ... incr gut Ca2+ absorption ... is inhibited by iron ... Disease #Signs #Symptoms ... #Pathophysiology
Suspected Celiac Disease - Diagnosis Algorithm

Celiac disease suspected:
 • Signs and symptoms of celiac disease
 •
Disease - Diagnosis Algorithm ... • Signs and symptoms ... celiac disease • Iron-deficiency ... without discernable cause ... Disease #Diagnosis #Algorithm
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
Algorithm regarding ... suspected HH based on symptoms ... out additional causes ... If other causes ... hemochromatosis #algorithm
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
Psychiatric symptoms ... deficiency can lead to iron ... , or any other cause ... #VitaminC #AscorbicAcid ... #Pathophysiology
Clozapine Toxicology
Clozapine is an atypical antipsychotic most often reserved for use in patients who have treatment-resistant
effect on negative symptoms ... Pharmacokinetics - Absorption ... absorbed with an oral bioavailability ... Clozapine is known to cause
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
enzyme 21-OHase causes ... maintains appropriate ion ... Signs/Symptoms/Complications ... #21HydroxylaseDeficiency #21OHD #pathophysiology
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
Abnormal Osteoclasts cause ... Skull expansion causes ... middle ear bones causes ... PagetsDisease #pathophysiology ... diagnosis #signs #symptoms