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diagnosis differential deficiency anemia causes nephrology pharmacology algorithm hematology pathophysiology management nutrition phosphate table comparison binders cardiology chf disease endocrinology
Pharmacology of diuretics Acetazolamide, Loop diuretics, Thiazide‐like diuretics, MRA, Amiloride Site of Action, Maximum Dose, Half-Life, Onset, Bioavailability,
Half-Life, Onset, Bioavailability ... , Absorption #
Iron - Possible Routes of Administration and Fate in the Organism #Iron #Absorption #Routes #Pathophysiology #pharmacology #Oral
Iron - Possible ... the Organism #Iron ... #Absorption #Routes
Causes of Iron Deficiency • Diet: ↓ Intake, e.g. vegan, Malnutrition, Polyphenol / tannins, ↓ Vitamin
Causes of Iron Deficiency ... Vitamin C • ↓ Absorption ... Others: Hemolysis, Iron ... @drkeithsiau #Iron
Causes of Iron Deficiency - Differential Diagnosis Algorithm • Blood loss: GI (cancer, ulcer, IBD), GU
Causes of Iron Deficiency ... Hemodialysis • Iron ... Lactation, Low iron ... Decreased ferrous iron ... loss of sites of absorption
Iron Deficiency in Heart Failure Pathophysiology: Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Iron Deficiency ... leads to decreased iron ... absorption and ... iron release Diagnosis ... Treatment - IV Iron
Causes of Iron Deficiency • Inadequate Intake: Vegetarian/vegan diet, Malnutrition • Increased Body Needs: Infants/preschoolers, Pregnancy,
Causes of Iron Deficiency ... Steroids • Reduced absorption ... IBD, cancer) #Iron
Gastrointestinal Evaluation of Iron Deficiency Anemia In patients with anemia, diagnose iron deficiency if: • Ferritin <
Evaluation of Iron ... anemia, diagnose iron ... Insufficient response to iron ... management #Iron ... Gastrointestinal #Evaluation #workup
Causes of Hyperferritinemia - Differential Diagnosis Ferritin > 1000 Ferritin is the storage form of iron. Increased hepcidin
storage form of iron ... cause increased GI absorption ... of iron. ... Iron overload - ... differentiate iron
Pancytopenia - Differential Diagnosis Algorithm • 12-13 g/dL, • ANC < 1800/uL, • platelet < 150,000/uL Initial
/uL Initial Workup ... LDH, ESR, CRP, iron ... Algorithm #hematology #workup
Workup for Hyperphosphatemia - Differential Diagnosis Framework Rule out spurious hyperphosphatemia: paraproteinemia, hyperlipidemia, hemolysis, hyperbilirubinemia, liposomal amphotericin
Workup for Hyperphosphatemia ... Renal Phosphate Absorption ... Diagnosis #Framework #Workup
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