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diagnosis differential management anticoagulation comparison treatment afib chads2 chads2vasc lupus score stroke table workup acid adverseeffects algorithm arterial autoimmune benefits
Stroke and bleeding risk stratification with the CHADS2-VASc and HAS-BLED schemas #Diagnosis #Hematology #CHADS2 #CHADS2VASc #HASBLED #Comparison
Stroke and bleeding ... risk stratification ... #Diagnosis #Hematology ... CHADS2 #CHADS2VASc #HASBLED ... #Stroke #Bleed
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 Bleeding risk calculators - HAS-BLED (atrial fibrillation) and IMPROVE (VTE prophylaxis for inpatients) Important notes: • No
Bleeding risk calculators ... - HAS-BLED (atrial ... risk tools have ... risk #HASBLED ... Anticoagulation #Factors #Hematology
CHA2DS2VASc vs HAS-BLED scores for stroke risk and bleed risk on anticoagulation C Congestive Heart Failure 1 H Hypertension 1 A2 Age >75 2 D Diabetes Mellitus 1 S2 Stroke,
CHA2DS2VASc vs HAS-BLED ... and bleed risk ... S Stroke 1 B Bleeding ... CHADS2 #CHADS2VASc #HASBLED ... AFib #Diagnosis #Hematology
Tranexamic Acid - Indications and Pharmacology Pharmacokinetics: • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
Indications and Pharmacology ... Hemoptysis, GI Bleeding ... fatigue; Increases risk ... #Indications #Pharmacology ... #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- History of bleeding ... epistaxis, gingival bleeding ... l MD SOAP) - Risks ... or if a primary hematologic ... #Workup #hematology
Clinically Significant Cardiovascular Drug-Drug Interactions With OTC Supplements and Herbal Products Angiotensin-Converting Enzyme Inhibitors (ACEIs) • Night-blooming
palmetto - Increases bleeding ... to increased bleed ... vera, Licorice - Causes ... palmetto - Increases bleeding ... supplementals #herbal #pharmacology
Hydroxychloroquine - Risks and Benefits in Lupus Benefits: ↓ Disease activity, ↓ Flare, ↓ Damage, ↓ Corticosteroid dose,
Hydroxychloroquine - Risks ... other medications leading ... rare with ~100 cases ... Benefits #Lupus #pharmacology ... #sideeffects #rheumatology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Findings: • Bleeding ... protein C and S Pathophysiology ... Treat primary cause ... Coagulation #diagnosis #causes ... treatment #management #hematology
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
• Consistent bleeding ... normal in mild cases ... Treatment - Acute Bleeding ... risk ... Management #treatment #hematology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
transfused patientsl • Risk ... blood donor • Pathophysiology ... without other cause ... transfused patients • Risk ... Transfusion #Reactions #hematology
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