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signs symptoms management rheumatology dermatology neurology causes algorithm syndrome endocrinology hepatology hypertension pathophysiology physicalexam radiology secondary abnormal ctchest cutaneous dermatomyositis
Woltman’s sign on Physical Exam 53-year-old man presented with fatigue and sensitivity to cold. A physical examination
evaluation confirmed a diagnosis ... of primary hypothyroidism ... is a neurologic manifestation ... of hypothyroidism ... Reflexes #Delayed #Clinical
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 Approach to Thyroid Function Tests in the Evaluation of Hyperthyroidism • Low TSH, Low normal T4
Evaluation of Hyperthyroidism ... of pregnancy, critical ... → Signs of ... ophthalmopathy → Graves' Disease ... #algorithm #diagnosis
Hyperthyroidism Overview Clinical Manifestation of Hyperthyroidism: • Fatigue • Weight loss • Heat intolerance • Depression, nervousness
Overview Clinical ... Manifestation of ... Diagnosis: ... #differential # ... endocrinology #signs
Characteristic clinical manifestations of Down syndrome Typical craniofacial appearance • Round face and flat
Characteristic clinical ... manifestations ... Increased risk of hypothyroidism ... PhysicalExam #Features #Signs ... #Manifestations
Gaucher Disease Pathophsiology • Lysosomal storage disorder • Deficiency of ß-glucocerebrosidase • Accumulation of glucosylceramide in macrophages Diagnosis
Gaucher Disease ... in macrophages Diagnosis ... in GBA1 gene Clinical ... Manifestations ... #Diagnosis #Signs
CLINICAL MANIFESTATIONS OF ADRENAL INSUFFICIENCY. Primary and secondary adrenal insufficiency: - Tiredness, weakness, mental depression
CLINICAL MANIFESTATIONS ... Autoimmune thyroid disease ... - Secondary hypothyroidism ... Insufficiency #Signs
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
Cutaneous manifestations ... appearing during the disease ... myelodysplastic #syndrome #differential ... #diagnosis #dermatology ... #oncology #clinical
Dermatological semiology of Cutaneous Vasculitis Clinicopathologic correlations • Purpura, papules, pustules, necrosis: involvement of small vessels
Connective tissue disease ... dermatology #semiology #signs ... #lesions #diagnosis ... #clinical #manifestations ... pathology #lesions #differential
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Manifestations ... (aPL) 30-45% Differential ... auto-immune, Infectious diseases ... sclerosis, Still's disease ... autoantibodies #signs
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
Optica (NMO) - Clinical ... Manifestations ... #Optica #NMO #Manifestations ... #diagnosis #neurology ... #symptoms #signs
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