41 results
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... /systemic sclerosis ... Treatment: • ... Summary #diagnosis #rheumatology ... #management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... life-threatening • Treatment ... : Chronic disease ... #lupus #Systemic ... #Summary #rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
microscopy and serial ... erythematosus (SLE ... : Lupus (SLE), Systemic ... , Interstitial Pulmonary ... ANA #patterns #rheumatology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad ... solid cancers • Systemic ... hepatitis • Pulmonary ... #diagnosis #management ... #treatment #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Cerebrovascular Disease ... autoantibodies that will cause ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome - Treatment ... Ulcers: • Treatment ... : • Systemic steroids ... #management #pharmacology ... #rheumatology
Treatment of Stable Narrow-Complex Tachycardia
Regular Rhythm:
 • Attempt vagal maneuvers
 • Give adenosine 6 milligrams IV
Treatment of Stable ... disease or CHF) ... Treat underlying cause ... disease or CHF) ... #management #cardiology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Discontinuation of causal ... months to years) Systemic ... : Chronic disease ... comparison #table #rheumatology ... #diagnosis #management
Leptospirosis
Pathogen: Leptospira (interrogans, kirschneri, noguchii)
Risk Factors:
 • Occupational exposure - Farmers, ranchers, trappers, veterinarians
 • Recreational
canoeing, kayaking, trail ... rainwater catchment systems ... failure • Severe pulmonary ... microbiology #diagnosis #treatment ... #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
highly inflammatory disease ... erythematosus [SLE ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology