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Blood Product Transfusion Components by Dr. Lizzy Hastie @LizzyHastie #BloodProducts #Transfusion #Components
Blood Product Transfusion ... LizzyHastie #BloodProducts ... #Transfusion #Components
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care TRICC - NEJM 1999 -
Evidence Summary for Transfusion ... unnecessary and cause ... Unnecessary transfusions ... Transfusions should ... Transfusions are
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... Transfusion Thresholds ... Causes purpura & ... TRALI): Leading cause ... more likely to cause
Hemolysis Classification - Intrinsic and Extrinsic Causes Commentary: Another way to think of immune hemolysis would be
and Extrinsic Causes ... autoimmune (most of the causes ... hemolysis, hemolytic transfusion ... Intrinsic #Extrinsic #Differential ... #Diagnosis #Causes
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion ... Non-Hemolytic Transfusion ... Causes purpura & ... TRALI): Leading cause ... more likely to cause
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... Anemia Intrinsic Causes ... prosthetic valve • Transfusion ... Hemolytic #Anemia #Differential ... #Diagnosis #causes
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
Causes of False ... Content • RBC Transfusions ... Effect • RBC Transfusions ... Diagnosis #DM2 #Differential
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... HUS) • Other: Transfusion ... implicated) - Transfusion ... Extravascular #Causes ... #differential #
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... injury • Blood transfusion ... Blood transfusion ... #hyperkalemia #differential ... #diagnosis #causes
Causes of HyperKalemia - Differential Diagnosis Increased extracellular K+: • Tissue injury • Hemolysis • Rhabdomyolysis •
Causes of HyperKalemia ... - Differential ... intake • Blood transfusion ... #HyperKalemia #Differential ... #Diagnosis #Causes
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