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diagnosis hematology management algorithm anemia classification hemolytic reactions blood product vasculitis acronym acute anesthesia anesthesiology arthritis autoimmune cardiology checklist clues
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care TRICC - NEJM 1999 -
Thresholds in Critical ... unnecessary and cause ... Transfusions should ... Transfusions are ... #Thresholds #Hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Transfusion Thresholds ... S/sx: Fever, flank ... Causes purpura & ... TRALI): Leading cause ... Sx include: fever
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
S/sx: Fever, flank ... have drop in Hct, fever ... Causes purpura & ... TRALI): Leading cause ... Sx include: fever
Causes of Acute Onset Fever - Differential Diagnosis Algorithm Viral: • Rhinovirus • Influenza Virus • Parainfluenza
Causes of Acute ... Onset Fever - Differential ... Iatrogenic: • Transfusion ... #Differential # ... Diagnosis #Algorithm #causes
Differential Diagnosis - Noninfectious Causes of Fever CRITICAL DIAGNOSES: - Acute myocardial infarction - Pulmonary embolism or
Differential Diagnosis ... Noninfectious Causes ... insufficiency - Transfusion ... Noninfectious #Causes ... #Differential #
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
TRALI vs TACO - Transfusion ... without other cause ... explain symptoms • Fever ... pulmonary edema) • Fever ... #Reactions #hematology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... Anemia Intrinsic Causes ... prosthetic valve • Transfusion ... Hemolytic #Anemia #Differential ... classification #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... HUS) • Other: Transfusion ... Extravascular #Causes ... #differential # ... diagnosis #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Hemolytic Anemia - Differential ... disease, drugs, transfusions ... Recent travel/Fevers ... Hemolytic #Anemia #Differential ... Diagnosis #Algorithm #causes
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... mountain spotted fever ... Vasculopathy #Purpura #Differential ... #Diagnosis #hematology ... #rheumatology #
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