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diagnosis differential hematology algorithm hba1c @dharsaty approach color deficiency discoloration dm2 eas elevation false folate folicacid fructosamine glycatedproteins hemoglobina1c hgba1c
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
Causes of False ... Content • RBC Transfusions ... blood loss • Hemolytic ... anemia • Splenomegaly ... #Decrease #Diagnosis
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Diagnosis Algorithm Decreased ... WBCs - Decreased ... Bleed • Hemolysis ... Microangiopathic Hemolytic
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Diagnosis for Hemolytic ... Anemia Intrinsic ... prosthetic valve • Transfusion ... #Anemia #Differential ... #classification
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
Mild-to-moderate decrease ... in most cases; ... result in severe anemia ... Platelet count - Decreased ... anemia Indirect
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Chronic Disease Normal ... • Bleeding • Hemolysis ... #MCV #Classification ... Diagnosis #Algorithm #Causes
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
combination of: Decreased ... RBC Production - Normal ... / Decreased Reticulocytes ... #Classification ... Diagnosis #Algorithm #Causes
Hematology Algorithms Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms Anemia ... characterized by a decrease ... However, these thresholds ... These causes could ... Normal range11.5
Etiologies of Folate Deficiency • Decreased dietary intake - uncommon in this era • Increased requirements
Deficiency • Decreased ... pregnant have hemolytic ... anemia, or psoriasis ... folate that can cause ... tissue stores with normal
Causes Abnormal Urine Color - Differential Diagnosis Turbid White Urine (Albinuria): • Chyluria, Filariasis, Schistosomiasis, Malignancy, Phosphaturia,
Causes Abnormal ... Syndrome - UTI caused ... Intravascular hemolysis ... deficiency, sickle cell anemia ... , thalassemia, transfusion
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... nodosum • Immune hemolytic ... anemia • Pain ... ) Classification ... products that define normal
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