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diagnosis differential hyperkalemia hba1c hematology reactions @dharsaty algorithm allergy anemia blood comparison dm2 eas elevation extrinsic false fructosamine glycatedproteins hemoglobina1c
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
Causes of False ... Elevation == Decreased ... Content • RBC Transfusions ... blood loss • Hemolytic ... Effect • RBC Transfusions
Hemolysis Classification - Intrinsic and Extrinsic Causes Commentary: Another way to think of immune hemolysis would be
Hemolysis Classification ... and Extrinsic Causes ... autoimmune (most of the causes ... , hemolytic transfusion ... #Classification
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Transfusion Thresholds ... Hemolysis on labs ... Causes purpura & ... TRALI): Leading cause ... more likely to cause
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Diagnosis for Hemolytic ... Anemia Intrinsic Causes ... prosthetic valve • Transfusion ... udaygulati #Hemolytic ... #classification
Causes of HyperKalemia - Differential Diagnosis Increased extracellular K+: • Tissue injury • Hemolysis • Rhabdomyolysis •
Causes of HyperKalemia ... Tissue injury • Hemolysis ... intake • Blood transfusion ... of injection Decreased ... Differential #Diagnosis #Causes
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Allergen-specific lgE causes ... Examples: Acute transfusion ... reaction, Haemolytic ... allergy #table #classification
Hemoglobin A1c (glycated hemoglobin) reflects the average blood glucose concentration over the course of the RBC
correlated with 35-76% decrease ... Women with HbA1c ... women with normal HgbA1c ... span, such as hemolytic ... frequent blood transfusions
Causes of Hyperkalemia Pseudohyperkalemia - Tourniquet use - Hemolysis (in vitro) - Leukocytosis - Thrombocytosis Intra- to extracellular
Causes of Hyperkalemia ... Tourniquet use - Hemolysis ... Potassium-containing drugs - Transfusion ... aged blood - Hemolysis ... tissue necrosis Decreased
Causes of Hyperkalemia l. Pseudohyperkalemia A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis B.
Causes of Hyperkalemia ... leukocytosis, in vitro hemolysis ... Decreased distal ... High #Potassium #Classification ... #Causes
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