11 results
diagnosis differential anemia management blood intravascular product reactions algorithm classification coagulation deficiency dic disseminated ebm extravascular folate folicacid hemolysis mentzerindex
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care TRICC - NEJM 1999 -
Thresholds in Critical ... unnecessary and cause ... Transfusions should ... Transfusions are ... #Thresholds #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... HUS) • Other: Transfusion ... implicated) - Transfusion ... Extravascular #Causes ... differential #diagnosis #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Transfusion Thresholds ... Causes purpura & ... TRALI): Leading cause ... more likely to cause ... diagnosis #management #hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Diagnosis Algorithm Decreased ... WBCs - Decreased ... Bleed • Hemolysis ... #Hematology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Diagnosis for Hemolytic ... Anemia Intrinsic Causes ... prosthetic valve • Transfusion ... udaygulati #Hemolytic ... classification #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
• Febrile Non-Hemolytic ... Causes purpura & ... TRALI): Leading cause ... more likely to cause ... diagnosis #management #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
Mild-to-moderate decrease ... in most cases; ... Platelet count - Decreased ... nucleated RBCs, and decreased ... Diagnosis #Workup #Hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
DIC/TTP/HUS - Hemolytic ... Fragility: • Decreased ... Differential #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Etiologies of Folate Deficiency • Decreased dietary intake - uncommon in this era • Increased requirements
Deficiency • Decreased ... pregnant have hemolytic ... folate that can cause ... anticonvulsants lead to increase ... differential #diagnosis #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
incompatible blood transfusion ... Treat primary cause ... hydration • RBC transfusion ... Coagulation #diagnosis #causes ... treatment #management #hematology
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