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diagnosis differential management algorithm hematology hyperkalemia nephrology workup cardiology potassium checklist classification criticalcare anemia anesthesia anesthesiology deficiency endocrinology high intraoperative
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
Causes of False ... Iron, B-12, or folate ... Reduction == Increase ... HgbA1c #Laboratory #Increase ... #Decrease #Diagnosis
Etiologies of Folate Deficiency • Decreased dietary intake - uncommon in this era • Increased requirements
Deficiency • Decreased ... in this era • Increased ... pregnant have hemolytic ... that can cause ... anticonvulsants lead to increase
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Transfusion Thresholds ... Hemolysis on labs ... Causes purpura & ... TRALI): Leading cause ... more likely to cause
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Diagnosis Algorithm Decreased ... WBCs - Decreased ... Infiltration - Increased ... Bleed • Hemolysis
Causes of HyperKalemia - Differential Diagnosis Increased extracellular K+: • Tissue injury • Hemolysis • Rhabdomyolysis •
Causes of HyperKalemia ... Differential Diagnosis Increased ... Tissue injury • Hemolysis ... intake • Blood transfusion ... of injection Decreased
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
venipuncture • Hemolysis ... - Transfusion ... hypoperfusion Increased ... Blood transfusion ... differential #diagnosis #causes
Folate Deficiency - Causes of Decreased Folic Acid ↓ Intake: Diet, Age, Alcohol ↑ Demand: Pregnancy, Infancy, Hemolysis,
Folate Deficiency ... - Causes of Decreased ... Pregnancy, Infancy, Hemolysis ... @drkeithsiau #Folate
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
Mild-to-moderate decrease ... in most cases; ... Platelet count - Decreased ... nucleated RBCs, and decreased ... hematuria (without casts
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
combination of: Decreased ... Hypochromic RBCs Decreased ... Production - Normal / Decreased ... Deficiency • B12/Folate ... Diagnosis #Algorithm #Causes
Hyperkalemia: Diagnostic algorithm Decreased renal potassium excretion • Acute renal failure • Chronic renal failure • Drugs Increased
Diagnostic algorithm Decreased ... failure • Drugs Increased ... diet • Blood transfusion ... • Tumor lysis/hemolysis
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