22 results
Causes of False Elevation and Reduction in HbA1c

== False Elevation ==
Decreased RBC turnover 
• Iron, B-12,
Causes of False ... Hypertriglyceridemia • Uremia High ... Content • RBC Transfusions ... blood loss • Hemolytic ... #Decrease #Diagnosis
Hemolysis Classification - Intrinsic and Extrinsic Causes

Commentary: Another way to think of immune hemolysis would be
and Extrinsic Causes ... autoimmune (most of the causes ... you have already listed ... , hemolytic transfusion ... Differential #Diagnosis #Causes
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Transfusion Thresholds ... Causes purpura & ... TRALI): Leading cause ... High mortality. ... more likely to cause
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
• Febrile Non-Hemolytic ... Causes purpura & ... TRALI): Leading cause ... High mortality. ... more likely to cause
Causes of HyperKalemia - Differential Diagnosis
Increased extracellular K+:
 • Tissue injury
 • Hemolysis
 • Rhabdomyolysis
 •
Causes of HyperKalemia ... Tissue injury • Hemolysis ... glycosides • High ... intake • Blood transfusion ... of injection Decreased
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
venipuncture • Hemolysis ... phlebotomy High ... - Transfusion ... differential #diagnosis #causes ... #potassium #high
Hyperkalemia: Diagnostic algorithm
Decreased renal potassium excretion
 • Acute renal failure
 • Chronic renal failure
 • Drugs
Increased
Diagnostic algorithm Decreased ... diet • Blood transfusion ... • Tumor lysis/hemolysis ... Normal, Renin High ... hypoplasia Aldosterone high
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
venipuncture • Hemolysis ... phlebotomy High ... - Transfusion ... differential #diagnosis #causes ... #potassium #high
Several artifacts can cause significant and potentially misleading alterations to measured RBC parameters: 
1. Old samples
falsely high Hgb ... Hemolysis causes ... PCV to decrease ... PCV and MCV to decrease ... Bite #Keratocyte #Blister
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
glomerulonephritis; HUS = hemolytic-uremic ... red blood cells/high-power ... cell/white cell casts ... each diagnosis cluster ... Nephrocalcinosis causes