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diagnosis differential hematology anemia hyperkalemia management blood nephrology potassium product classification comparison dm2 elevation extravascular false hba1c hemolysis hgba1c increase
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Transfusion Thresholds ... Transfusion Reaction ... Transfusion Reaction ... Transfusion Reaction ... High mortality.
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... HUS) • Other: Transfusion ... reaction, Paroxysmal ... reaction • Intrinsic ... Extravascular #Causes
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
Causes of False ... Hypertriglyceridemia • Uremia High ... Content • RBC Transfusions ... blood loss • Hemolytic ... #Decrease #Diagnosis
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Transfusion Reaction ... Transfusion Reaction ... Transfusion Reaction ... Causes purpura & ... High mortality.
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
phlebotomy High ... reactions Common ... reaction - Tumor ... differential #diagnosis #causes ... #potassium #high
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Diagnosis for Hemolytic ... prosthetic valve • Transfusion ... reactions ex. ... udaygulati #Hemolytic ... classification #hematology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
phlebotomy High ... reactions Common ... reaction - Tumor ... differential #diagnosis #causes ... #potassium #high
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
Reactions TRALI ... Critical illness, high ... , female of high ... without other cause ... #Reactions #hematology
Causes of HyperKalemia - Differential Diagnosis Increased extracellular K+: • Tissue injury • Hemolysis • Rhabdomyolysis •
Causes of HyperKalemia ... Tissue injury • Hemolysis ... glycosides • High ... intake • Blood transfusion ... of injection Decreased
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
DIC/TTP/HUS - Hemolytic ... Fragility: • Decreased ... fever • Drug reactions ... Differential #Diagnosis #hematology ... #nonpalpable #dermatology
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