22 results
diagnosis hematology treatment differential neurology criticalcare hyperkalemia syndrome algorithm blood cardiology endocrinology product reactions b12 bundle checklist classification clinica clinical
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
Causes of False ... Elevation == Decreased ... Content • RBC Transfusions ... blood loss • Hemolytic ... #Decrease #Diagnosis
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Transfusion Thresholds ... Causes purpura & ... TRALI): Leading cause ... more likely to cause ... #diagnosis #management
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
Normal or slightly elevated ... Mild-to-moderate decrease ... in most cases; ... Platelet count - Decreased ... or may not be elevated
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
• Febrile Non-Hemolytic ... Causes purpura & ... TRALI): Leading cause ... more likely to cause ... #diagnosis #management
Causes of HyperKalemia - Differential Diagnosis Increased extracellular K+: • Tissue injury • Hemolysis • Rhabdomyolysis •
Causes of HyperKalemia ... Tissue injury • Hemolysis ... intake • Blood transfusion ... of injection Decreased ... Differential #Diagnosis #Causes
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
incompatible blood transfusion ... fibrinogen • Elevated ... Treat primary cause ... hydration • RBC transfusion ... #treatment #management
Intracranial Hemorrhage (ICH) and Increased Intracranial Pressure (ICP) - Pathophysiology ICH Management: 1. Manage Blood Pressure •
Pathophysiology ICH Management ... consider platelet transfusion ... = dilated BV = raises ... Hemorrhage #ICH #elevated ... #neurosurgery #management
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... Diuretics, PRBC transfusion ... K, Elevated phos ... , Elevated uric ... TLS #diagnosis #management
Fever vs Hyperthermia Fever: • Regulated in the hypothalamic thermoregulatory center • "Set point" raised by prostaglandin
production and decrease ... the elevated hypothalamic ... rapidly fatal • Causes ... Identify underlying cause ... comparison #diagnosis #management
Ketosis Disorders Ketone bodies are a normal metabolic energy source. Excessive unregulated production of ketones, often accompanied
ketoacidosis (DKA) - caused ... (pH < 7.35) w/ elevated ... ketosis but marked increase ... Glucosuria causes ... differential #diagnosis #management
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