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diagnosis differential hematology hyperkalemia anemia nephrology algorithm classification hemolysis management potassium blood clinical hba1c high intravascular physicalexam product rheumatology signs
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Transfusion Thresholds ... Transfusion Reaction ... Transfusion Reaction ... Transfusion Reaction ... Causes purpura &
Hemolysis Classification - Intrinsic and Extrinsic Causes Commentary: Another way to think of immune hemolysis would be
and Extrinsic Causes ... autoimmune (most of the causes ... , hemolytic transfusion ... reactions) - Dr ... Differential #Diagnosis #Causes
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... HUS) • Other: Transfusion ... reaction, Paroxysmal ... reaction • Intrinsic ... Extravascular #Causes
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Transfusion Reaction ... Transfusion Reaction ... Transfusion Reaction ... Causes purpura & ... TRALI): Leading cause
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
Causes of False ... Elevation == Decreased ... Content • RBC Transfusions ... blood loss • Hemolytic ... #Decrease #Diagnosis
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Diagnosis Algorithm Decreased ... WBCs - Decreased ... Bleed • Hemolysis ... Anemias (MAHA) - Abnormal
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
venipuncture • Hemolysis ... reactions Common ... - Transfusion ... reaction - Tumor ... differential #diagnosis #causes
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Diagnosis for Hemolytic ... Anemia Intrinsic Causes ... prosthetic valve • Transfusion ... reactions ex. ... udaygulati #Hemolytic
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
venipuncture • Hemolysis ... reactions Common ... - Transfusion ... reaction - Tumor ... differential #diagnosis #causes
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... AIHA, Cold AIHA, Transfusion ... reactions, Drug-associated ... Blood Smear ↑ abnormal ... Urobilinogen #Hemolysis
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