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diagnosis checklist anesthesia anesthesiology intraoperative differential hematology hyperkalemia nephrology treatment blood criticalcare glomerular hemorrhage hyperthermia nephrotic neurology pressure product reactions
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
Causes of False ... Elevation == Decreased ... Content • RBC Transfusions ... blood loss • Hemolytic ... #Decrease #Diagnosis
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Transfusion Thresholds ... Causes purpura & ... TRALI): Leading cause ... more likely to cause ... #diagnosis #management
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
• Febrile Non-Hemolytic ... Causes purpura & ... TRALI): Leading cause ... more likely to cause ... #diagnosis #management
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
Mild-to-moderate decrease ... in most cases; ... Platelet count - Decreased ... nucleated RBCs, and decreased ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup
Causes of HyperKalemia - Differential Diagnosis Increased extracellular K+: • Tissue injury • Hemolysis • Rhabdomyolysis •
Causes of HyperKalemia ... Tissue injury • Hemolysis ... intake • Blood transfusion ... of injection Decreased ... Differential #Diagnosis #Causes
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia If prolonged or ≥ 39 C this is a
maintained fever CAUSES ... device • Blood transfusion ... #Differential #Causes ... Checklist #Diagnosis #Management ... #Workup
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
incompatible blood transfusion ... Treat primary cause ... hydration • RBC transfusion ... Coagulation #diagnosis #causes ... #treatment #management
Hypotension - Guidelines for Crises in Anaesthesia Hypotension is commonly due to unnecessarily deep anaesthesia, the autonomic
hypovolaemia or combined causes ... • Increase fresh ... pressure as a cause ... Checklist #Diagnosis #Management ... #Workup
Intracranial Hemorrhage (ICH) and Increased Intracranial Pressure (ICP) - Pathophysiology ICH Management: 1. Manage Blood Pressure •
Pathophysiology ICH Management ... ) because they increase ... consider platelet transfusion ... = dilated BV = raises ... #neurosurgery #management
Intraoperative Sepsis - Guidelines for Crises in Anaesthesia Severe sepsis (hypotension persisting after initial fluid challenge of
likely underlying cause ... of problem. ❷ Increase ... devices could have caused ... Discuss ongoing management ... #Workup
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