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diagnosis management differential hematology nephrology potassium blood high product reactions syndrome ebm encephalopathy k leukostasis lysis neurology posterior prbc pres
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care TRICC - NEJM 1999 -
Thresholds in Critical ... unnecessary and cause ... Transfusions should ... Transfusions are ... #Thresholds #Hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Transfusion Thresholds ... Causes purpura & ... TRALI): Leading cause ... Hypocalcemia, Hyperkalemia ... more likely to cause
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... injury • Blood transfusion ... Hemolysis - Transfusion ... Blood transfusion ... differential #diagnosis #causes
Causes of HyperKalemia - Differential Diagnosis Increased extracellular K+: • Tissue injury • Hemolysis • Rhabdomyolysis •
Causes of HyperKalemia ... intake • Blood transfusion ... MCW_Nephrology #HyperKalemia ... Differential #Diagnosis #Causes
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... injury • Blood transfusion ... Hemolysis - Transfusion ... Blood transfusion ... differential #diagnosis #causes
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion ... Causes purpura & ... TRALI): Leading cause ... Hypocalcemia, Hyperkalemia ... more likely to cause
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... Weakness, cramping, nausea ... ischemia, hemolysis, transfusions ... only if no clear cause ... #Hyperkalemia
Causes of Hyperkalemia Pseudohyperkalemia - Tourniquet use - Hemolysis (in vitro) - Leukocytosis - Thrombocytosis Intra- to extracellular
Causes of Hyperkalemia ... intoxication - Hyperkalemic ... Potassium-containing drugs - Transfusion ... acidosis) #Hyperkalemia ... #Causes #diagnosis
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... Diuretics, PRBC transfusion ... hydration - Hyperkalemia
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
emergency, Blood transfusion ... , Hypercalcemia ... the underlying cause ... with AEDs until cause
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