12 results
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care

TRICC - NEJM 1999 -
Thresholds in Critical ... unnecessary and cause ... Transfusions should ... Transfusions are ... #Thresholds #Hematology
Indications for Transfusion of Platelets in Neonates

#Management #Peds #Pediatrics #Platelets #Transfusion #Plateletpheresis #Thresholds #NonBleeding #Surgery
Indications for Transfusion ... of Platelets in ... Peds #Pediatrics #Platelets ... #Transfusion #Plateletpheresis ... #Thresholds #NonBleeding
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Indications for Transfusion
Packed RBCs
 • Hgb <7 g/dL or hematocrit <21% in a patient with uncompromised
Indications for Transfusion ... hemoglobinopathy Platelets ... Platelet transfusions ... Willebrand disease #Transfusion ... #Indications #Thresholds
Thresholds for Transfusion of Platelets in Adults
Major surgery or invasive procedure, no active bleeding - 
≤
Thresholds for Transfusion ... of Platelets in ... #Management #Platelets ... #Transfusion #Plateletpheresis ... #Thresholds #NonBleeding
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Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Transfusion Thresholds ... donor (apheresis) platelets ... Causes purpura & ... TRALI): Leading cause ... more likely to cause
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
, due to anti-platelet ... Causes purpura & ... TRALI): Leading cause ... common following platelet ... more likely to cause
PLATELETS Mnemonic for Causes of Thrombocytopenia

P - Platelet Disorders (DIC, ITP, TTP)
L - Leukemia, Lymphoma
A -
PLATELETS Mnemonic ... for Causes of Thrombocytopenia ... P - Platelet ... Anemia T - Trauma, Transfusion ... S - Sepsis #PLATELETS
Procedure Risks and Platelet Targets for Transfusion
LOW RISK - Transfuse ≥ 20,000/uL
 • Paracentesis, EGD or
Procedure Risks and Platelet ... Targets for Transfusion ... Aguila @enrrikke #Platelet ... #Transfusion #thresholds
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
incompatible blood transfusion ... Findings in DIC: • Platelet ... Thrombocytopenia - Platelet ... Treat primary cause ... hydration • RBC transfusion
Intracranial Hemorrhage (ICH) and Increased Intracranial Pressure (ICP) - Pathophysiology
ICH Management:
1. Manage Blood Pressure
  •
Sulfate • If platelets ... 100: consider platelet ... transfusion 4. ... = dilated BV = raises