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diagnosis differential endocrinology hypercalcemia hypocalcemia management clinical hematology nephrology treatment apl associated auerrods blood bloodsmear breast calcium cardiology chf criticalcare
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
with occasional Auer ... consistent with Auer ... addition to APL, Auer ... maturation, and mixed lineage ... #Clinical #Path
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 Causes of Hypocalcemia - Differential Diagnosis Algorithm • Extravascular: Pancreatitis, surgery, acute phosphate intake and renal
Causes of Hypocalcemia ... Differential Diagnosis Algorithm ... Hyperphosphatemia, High PTH ... Hyperphosphatemia, Low PTH ... #Causes #algorithm
Hypercalcemia - Differential Diagnosis Algorithm Elevated PTH (High or normal): • Primary Hyperparathyroidism • Familial Hypocalciuric Hypercalcemia Low
Differential Diagnosis Algorithm ... Elevated PTH (High ... Hypercalcemia Low PTH ... Differential #Diagnosis #Algorithm ... #causes #endocrinology
Hypercalcemia Workup and Differential Diagnosis Framework 1) Determine whether PTH-dependent 2) Assess for other hormonal causes 3) Assess for
Determine whether PTH-dependent ... other hormonal causes ... for non-hormonal causes ... Differential #Diagnosis #algorithm
Hypocalcemia - Differential Diagnosis Algorithm • Low Serum Mg: GI losses, Renal losses, Alcoholism, Malnutrition, Drug-Induced
Differential Diagnosis Algorithm ... Drug-Induced • Intact PTH ... sunlight • Other Causes ... Differential #Diagnosis #Algorithm ... #causes
Breast Discharge - Differential Diagnosis Algorithm High Prolactin + Normal TSH • Microprolactinoma • Steroid Hormone Intake
Differential Diagnosis Algorithm ... Contraceptive Pill/Patch ... Differential #Diagnosis #Algorithm ... Endocrinology #Causes
Causes of Hypomagnesemia - Differential Diagnosis Algorithm GI LOSS - FeMg < 2-2.5% or 24h Urine Mg
Causes of Hypomagnesemia ... Differential Diagnosis Algorithm ... Hypercalcemia-PTH ... Magnesium #Low #Causes ... Differential #Diagnosis #Algorithm
Hypophosphatemia - Differential Diagnosis Algorithm • Decreased intake/absorption: Starvation, Alcoholism, Malabsorption, Phosphate binder use • Redistribution/
Differential Diagnosis Algorithm ... losses: FGF23, PTH ... Differential #Diagnosis #Algorithm ... #causes #nephrology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Lymphocytes - T or B lineage ... ALL is of B-cell lineage ... -> AML: Blast crises ... Pruritis after hot bath ... Age: 50-60 • Auer
Causes of Nephrolithiasis - Differential Diagnosis Algorithm Radio-opaque - Calcium-containing - 90% of stones Radiolucent - Non-calcium 10%
Causes of Nephrolithiasis ... Differential Diagnosis Algorithm ... • Increased PTH ... Differential #Diagnosis #Algorithm ... #Causes
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