156 results
Osteoporosis: Pathogenesis and risk factors

 • Age > 30 (post-peak bone mass)
 • Post-menopausal women ->
30 (post-peak bone ... Leukemia) • GI diseases ... liver or kidney disease ... #Osteoporosis #pathophysiology ... #signs #symptoms
Stress Fracture: Pathogenesis and clinical findings
Abnormal biomechanics, Repetitive impact activities
=> Repetitive subthreshold mechanical loading
=> Bone strain
=>
mechanical loading => Bone ... strain => Bone ... StressFractures #msk ... #orthopedics #pathophysiology ... #symptoms #signs
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Most common symptoms ... - Bone symptoms ... granulamatous disease ... - Infiltrative diseases ... Other biliary diseases
Meralgia paresthetica: Pathogenesis and Clinical Findings
Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica
 •
paresthetica • Symptoms ... 3-6 months of symptom ... intervertebral disc disease ... MeralgiaParesthetica #MSK ... #pathophysiology
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Gaucher Disease ... Pathophsiology ... Osteonecrosis, bone ... #Gauchers #Disease ... Diagnosis #Signs #Symptoms
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Weakness, Incr CK • Bone ... Erythematosus #SLE #MSK ... Complications #pathophysiology ... #signs #symptoms
Spondylosis - Pathogenesis and Complications

Vertebral disease that may compress the vertebral canal from all sides
Note: Do
Complications Vertebral disease ... #Spondylosis #pathophysiology ... #msk #complications
Patellofemoral Syndrome - Pathogenesis and clinical findings
 • Anterior Knee Pain with possible symptoms of 'catching'
with possible symptoms ... Patellofemoral #Syndrome #pathophysiology ... diagnosis #signs #symptoms ... #msk
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
tear a portion of bone ... lateral hip Signs/Symptoms ... FemoralHead #Fractures #msk ... #diagnosis #pathophysiology ... #signs #symptoms
A schema of the pathophysiology of the inborn errors of metabolism, excluding complex storage diseases. Helps
schema of the pathophysiology ... complex storage diseases ... connections and pathophysiology ... images/5172 Source ... MetabolicEmergency #Genetics #Pathophysiology