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diagnosis management differential symptoms signs algorithm clinical treatment endocrinology rheumatology causes pathophysiology cardiology hematology pulmonary ibd oncology physicalexam syndrome video
Fatigue and IBD Algorithm • 40-50% patients have fatigue despite clinical remission • Risk factors: BMI,
Fatigue and IBD ... patients have fatigue ... disturbance, Female, Thiopurine ... 20% w/ improved fatigue ... Waseem_AhmedMD #Fatigue
IBD - Assessment of Lack of Response (sLOR) - Differential Diagnosis Non-inflammatory mechanisms: • IBS • Fibrostenotic
#Inflammatory #BowelDisease
Persistent UC Symptoms Despite 5-ASA Therapies • Assess for Drug Adherence • Disease Activity Assessment (bloody
options: - Thiopurines
Thiopurines in IBD Indications: • Steroid-sparing agents indicated for maintenance of remission in UC and CD •
Thiopurines in IBD ... Metabolism: • Thiopurine ... activity: avoid thiopurines ... 1.5mg/kg TDM (thiopurine ... #Inflammatory #BowelDisease
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Causes of Fatigue ... Idiopathic • Chronic Fatigue ... Syndrome #Chronic #Fatigue
Treatment Schema for Standard-Risk Acute Lymphoblastic Leukemia Induction: • Vincristine, Steroid (dexamethasone), L-Asparaginase, Intrathecal (IT) methotrexate Consolidation
Vincristine, Steroid, Thiopurine
Hypothyroidism and Hyperthyroidism - Symptoms and Signs Hypothyroidism: - General - From asymptomatic to myxedema coma, “Like
Memory loss • Fatigue ... energy but are fatigued
Paradoxic Breathing in Pediatric Respiratory Distress - Improved after nebulizers and HFNC Inward chest wall movement with
ventilation muscle fatigue
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 Hypopituitarism Differential Diagnosis Algorithm Suspected hypopituitarism (anterior pituitary) Symptoms: fatigue, depression, and other endocrine dysfunction ARUPConsult @ARUPLabs #Hypopituitarism #Differential #Diagnosis
pituitary) Symptoms: fatigue
Approach to Leukocytosis - Differential Diagnosis Algorithm Features of hematologic malignancy: • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
bruising/bleeding, fatigue
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