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diagnosis causes orthopedics msk hematology workup endocrinology clinical hepatology hypercalcemia management anemia fractures pancytopenia radiology signs symptoms alkaline alp bony
Rheumatoid arthritis (RA): X-ray features • Soft tissue swelling (best seen by comparing left & right
Narrowing • Bony ... the articular bone ... Peri-articular osteopenia (bones ... Radiology #Clinical #Pathophysiology
Hypercalcemia - Hormones and Pathophysiology Calcitriol: • Bones: Enhances mineralization • GI Tract: ↑ Ca2+
Calcitriol: • Bones ... PO4- PTH: • Bones ... : ↑ Bone resorption ... Calcitonin: • Bones ... : ↓ Bone resorption
Hyperparathyroidism - Primary vs Secondary vs Tertiary Lab Comparison: • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
signs, Fragile bones ... easily/weakness, Bone ... Secondary #Tertiary #pathophysiology
Pancytopenia - Differential Algorithm / Schema - Bone Marrow Failure - Bone Marrow Infiltration - Sequestration / Destruction #Pancytopenia #Differential
Pancytopenia - Differential ... Algorithm / Schema ... - Bone Marrow ... Failure - Bone ... #Algorithm #Schema
Thrombocytopenia - Differential Diagnosis Algorithm Decreased production: • Bone marrow suppression • Bone marrow failure • Bone
Thrombocytopenia - Differential ... Diagnosis Algorithm ... production: • Bone ... suppression • Bone ... marrow failure • Bone
Pathophysiology of Menopause Organ System Changes: - CNS / Vasomotor Instability - Urogenital Mucosa - Cardiovascular - Bones #Pathophysiology #Menopause #Changes
Pathophysiology ... Cardiovascular - Bones ... #Pathophysiology
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Causes of Bone/Joint ... Generally affects long bones ... • Differentiate ... BrighamChiefs #Bone ... SickleCell #Disease #differential
Bone Lesion on X-Ray - Differential Diagnosis Algorithm Exostotic • Osteochondroma Asymptomatic &/or Non-Active Bone Scam •
Bone Lesion on X-Ray ... - Differential ... /or Non-Active Bone ... • Unicameral Bone ... • Aneurysmal Bone
Hypercalcemia of Malignancy - Pathophysiology PTH-mediated • Parathyroid cancer • Ectopic production: Small cell lung cancer, ovarian
of Malignancy - Pathophysiology ... resorption in the bone ... resorption in the bone ... #Differential # ... Diagnosis #algorithm
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
synthesized in: liver, bone ... • softening of bones ... of feet, thigh bones ... : Inhibitor of bone ... Skeletal: - Bone
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