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diagnosis hematology rheumatology anemia skinrash ulcerative ulcers agglutinin approach bleeding bruising champs clinicopathology cold compared comparison cryoglobulinemia cryoglobulins disease erythemas
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... Types: • Type ... • Low serum C4 complement ... #classification
Vascular Skin Lesions - Differential Diagnosis Algorithm - Petechiae < 0.2 cm diameter - Purpura 0.2
Skin Lesions - Differential ... Diagnosis Algorithm ... #SkinRash #dermatology ... #Differential # ... #causes
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low Complement ... Glomerulonephritis #Vasculitis ... #differential # ... diagnosis #algorithm
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... - Differential ... Diagnosis Algorithm ... HUS • DIC • Vasculitis ... #Causes #Hematology
Skin Ulcers of the Lower Legs / Feet - Differential Diagnosis Algorithm Physical: • Pressure • Trauma • Radiation Vascular: • Arterial
Legs / Feet - Differential ... Diagnosis Algorithm ... insufficiency • Vasculitis ... ulcerative #skinrash #dermatology ... #causes
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... 1 (50%-80%), type ... Hypocomplementemia #Low #Complement ... Mnemonic #diagnosis #differential ... #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Diagnosis Algorithm ... perfringens - Complement-Mediated ... #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... / Bruising - Differential ... Diagnosis Algorithm ... • Steroids • Vasculitis ... #Causes #Hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential ... tract, and often causes ... against MPO • Complement ... differential #diagnosis ... #rheumatology #classification
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Volume (MCV) - Differential ... Diagnosis Algorithm ... #Anemia #MCV #Classification ... #Causes #Hematology
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