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differential vasculitis lupus management patterns workup antibody aortitis arthritis autoantibodies conditions cryoglobulinemia cryoglobulins extrarticular igg4 joint laboratory phenotypes related sjogrens
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Rheumatic Diseases ... • Rheumatic Diseases ... , Interstitial Pulmonary ... #Antibodies #ANA
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... Associated Rheumatic ... Diseases: • Homogeneous ... tissue disease ... #Antibodies #ANA
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... connective tissue disease ... #ANCA #Antineutrophil ... #antibodies #diagnosis ... diseases
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
), ANCA associated ... vasculitis (rare) • Rheumatic ... Diseases: IgG4- ... Related Disease ... (IgG4-RD), Rheumatoid
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
• Rheumatic ... • Interstitial lung ... , SLE • Pulmonary ... , SLE, Rheumatic ... stenosis - Rheumatic
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... findings (ANA, ... vasculitis, rheumatoid ... Serositis Labs: • ANA ... #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
disease, and ocular ... • Kawasaki Disease ... (Granulomatous disease ... : Systemic rheumatic ... diseases, such
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... Association with disease ... with auto-immune diseases ... #diagnosis #rheumatology ... #table #ANA
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Diseases • Septic ... (SLE) - Antinuclear ... exclude inflammatory disease ... connective-tissue disease ... #Disease #Rheumatoid
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Autoimmune diseases ... respectively, having rheumatoid ... Elevated serum rheumatoid ... DDX: • ANCA (Antineutrophil ... (SLE), rheumatoid
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