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differential management antinuclear classification workup anca antineutrophil aortitis arthritis conditions cryoglobulinemia cryoglobulins extrarticular joint laboratory macrophage mas pain patterns phenotypes
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
lupus erythematosus ... lupus erythematosus ... : Lupus (SLE), Systemic ... , Interstitial Pulmonary ... #rheumatology #diagnosis
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Non-Infectious Aortitis: • Vasculitides ... associated vasculitis ... : IgG4-Related Disease ... lupus erythematosus ... #rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
) • Systemic lupus ... Vasculitis: • ... Renal-limited vasculitis ... #antibodies #diagnosis ... #rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... vasculitis, rheumatoid ... • Mesenteric vasculitis ... inflammation Cutaneous Vasculitis ... #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
disease, and ocular ... diseases, such ... as systemic lupus ... , and SLE) • Urinalysis ... #rheumatology #
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
of Systemic Lupus ... Butterfly rash, Vasculitis ... pain (20%) Renal disease ... #SLE #systemic ... #diagnosis #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
multisystemic disease ... demyelinating disease ... ) • Cutaneous vasculitis ... Vasculitis: • ... #Rheumatology #
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
• Interstitial lung ... , SLE • Pulmonary ... Antiphospholipid-antibody ... Vasculitis (e.g. ... #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Autoimmune diseases ... • Vasculitis ... lupus erythematosus ... classification #rheumatology ... #vasculitis
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Systemic lupus ... lupus erythematosus ... #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
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