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differential associations classification diseases table algorithm antibody antineutrophil aortitis cryoglobulinemia cryoglobulins dermatology lupus management patterns petechiae petechial physicalexam rash syndrome
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... in drug-induced SLE ... Vasculitis: • ... Renal-limited vasculitis ... #antibodies #diagnosis
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Autoantibodies and ... Disease Associations ANA ... Graves' disease c-ANCA ... - Vasculitis, e.g ... - Vasculitis, e.g
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Lupus (SLE): ANA ... others (RNP, aPL antibodies ... Vasculitis: P-ANCA ... perinuclear), C-ANCA ... diagnosis #associations
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... (SLE), Sjogren's ... , Interstitial Pulmonary ... #Antibodies #ANA ... #patterns #rheumatology
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Non-Infectious Aortitis: • Vasculitides ... ), ANCA associated ... vasculitis (rare ... (SLE), Sarcoidosis ... #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitis and Vasculitides ... often causes arthritis ... Vasculitis: + MPO-ANCA ... , and SLE) • Urinalysis ... #rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
vasculitis, rheumatoid ... • Mesenteric vasculitis ... inflammation Cutaneous Vasculitis ... • (-) ANA + (+ ... #Diagnosis #Rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
DDX: • ANCA (Antineutrophil ... • IgA vasculitis ... • Vasculitis ... (SLE), rheumatoid ... #vasculitis
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Infection - Vasculitis ... lesions • Severe pain ... - Autoimmune Vasculitis ... (lupus, RA, Sjogren's ... , rheumatoid factor
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
rheumatic diseases ... , such as SLE, atherosclerotic ... ischemia • Skin: Erythematous ... often causes arthritis ... #Rheumatology
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