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management vasculitis classification lupus patterns systemic antineutrophil aortitis arthritis autoantibodies conditions cryoglobulinemia cryoglobulins disease extrarticular joint laboratory myelitis neurology polychondritis
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... Antibody) and ANCA ... in drug-induced SLE ... #Antinuclear #Antibody ... #antibodies #diagnosis
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... (SLE), Sjogren's ... #Antibodies #ANA ... #patterns #rheumatology ... #diagnosis #differential
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Antibody refers ... (SLE), Sjogren's ... #Antibodies #ANA ... #diagnosis #differential
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... searched for when ANA ... Systemic #lupus #erythematosus ... #diagnosis #rheumatology ... #table #ANA
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
alopecia Differential ... Diagnosis: • ANCA-associated ... dermatomyositis, Sjogren ... Serositis Labs: • ANA ... #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often causes arthritis ... LFT • ESR • ANA ... ) pattern: antibodies ... SLE) • Urinalysis ... #diagnosis #rheumatology
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Diagnosis Framework ... ), ANCA associated ... Systemic lupus erythematosus ... (SLE), Sarcoidosis ... #Diagnosis #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
(SLE) - Antinuclear ... antibody (ANA) ... antibodies, which ... , a negative ANA ... multiple myeloma) • ANA
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... ab • RF • Antinuclear ... Hypocomplementemia • Can cause ... : • 10%-15% Pulmonary ... #Syndrome #Rheumatology
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Pulmonary ... • Pulmonary ... Antiphospholipid-antibody ... #differential # ... diagnosis #rheumatology
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