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differential classification antineutrophil aortitis associations autoantibodies conditions cryoglobulinemia cryoglobulins diseases extrarticular joint laboratory management table testing types workup
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Rheumatic Diseases ... • Rheumatic Diseases ... : Lupus (SLE), Systemic ... #patterns #rheumatology
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... Associated Rheumatic ... (SLE), Sjogren's ... #Antibodies #ANA ... #patterns #rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... ) • Systemic lupus ... • Sjögren syndrome ... Vasculitis: • ... #antibodies #diagnosis
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
), ANCA associated ... vasculitis (rare ... ) • Rheumatic Diseases ... Systemic lupus ... erythematosus (SLE
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
• Lupus (SLE): ... ANA (anti-nuclear ... others (RNP, aPL antibodies ... ribonucleoprotein) • RA: Rheumatoid ... Vasculitis: P-ANCA
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often causes arthritis ... Vasculitis: + MPO-ANCA ... : Systemic rheumatic ... as systemic lupus ... ) pattern: antibodies
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
• Rheumatic ... Rheumatic fever ... Vasculitis (e.g. ... stenosis - Rheumatic ... endocarditis, Rheumatic
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Elevated serum rheumatoid ... DDX: • ANCA (Antineutrophil ... lupus erythematosus ... (SLE), rheumatoid ... arthritis, Sjögren's
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... vasculitis, rheumatoid ... • Mesenteric vasculitis ... inflammation Cutaneous Vasculitis ... #Diagnosis #Rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis: • Systemic ... rheumatic diseases ... , such as SLE, atherosclerotic ... often causes arthritis ... #Rheumatology
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