1783 results
diagnosis differential management algorithm causes clinical disease treatment radiology neurology pulmonary pathophysiology cardiology hematology rheumatology infections nephrology table physicalexam signs
ANCA-Associated Vasculitis A group of necrotizing, small-vessel vasculitis without immune complex deposition. Complement levels are normal due
ANCA-Associated ... - C-ANCA pattern ... PR3 Anti-GBM disease ... Associated #Vasculitis #CANCA ... #PANCA #MPO #PR3
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Antibody) and ANCA ... connective tissue disease ... 90% • Anti-GBM disease ... - MPO>PR3 - ANCA ... #rheumatology #diseases
Renal diseases associated with endothelial injury@NatRevNeph #hemolyticuremicsyndrome #lupusnephritis #anca #Visualabstract #nephrology
Renal diseases associated ... lupusnephritis #anca
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Autoantibodies and their Disease ... c-ANCA - Vasculitis ... granulomatosis p-ANCA ... (TTG) - Celiac disease ... #Associations #diseases
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
pain • Kawasaki Disease ... (Granulomatous disease ... well as inner ear disease ... atherosclerotic disease ... most important diseases
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
nodosa - Buerger disease ... - Kawasaki disease ... small vessels - ANCA-associated ... and infectious diseases ... - serum disease
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
involvement: Anti-GBM Disease ... Negative IF): • PR3-ANCA ... (C-ANCA): GPA > ... > eGPA • MPO-ANCA ... (P-ANCA): eGPA,
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Peripheral edema, Disease-specific ... vasculitis, Behcet disease ... Goodpasture's Disease ... dysmorphic RBCs) • Disease-specific ... testing: anti-ANCA
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis 90%: -
glomerulonephritis 90%: - ANCA ... Vasculitis - Anti-GBM Disease ... Double Positive (ANCA ... Vasculitis, Behcet's Disease ... , mitral valve disease
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
and less common diseases ... Vogt-Koyanagi-Harada (VKH) disease ... polychondritis • Behcet disease ... spectrum disorder • ANCA-associated
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