40 results
Algorithm for the differentiation between simple and complex febrile seizures. Guidelines for evaluation of each. #Diagnosis
between simple and complex ... Management #EM #Neuro ... Seizure #Algorithm #Workup ... #Simple #Complex
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... Manifestations • Immune Complex ... Myopathy (Also caused ... #Systemic #Lupus ... Complications #pathophysiology
Type III Hypersensitivity: Pathogenesis and clinical findings
Definition: Small antigen-antibody complexes (produced from normal immune response to
antigen-antibody complexes ... self-antigens are the cause ... : • Systemic Lupus ... antigens are the cause ... Allergy #Immunology #pathophysiology
Glomerulonephritis - Differential Diagnosis Framework
ANCA:
 • C-ANCA: GPA (Wegener's)
 • P-ANCA: Microscopic Polyangiitis, Eosinophilic GPA (Churg
Anti-GBM Immune Complex ... Membranoproliferative • ↓C4: Lupus ... diagnosis #nephrology #causes
Mechanical Bowel Obstruction and Ileus - Pathogenesis and Clinical Findings
Ileus: Functional bowel "blockage", no peristalsis
Mechanical Obstruction:
of bowel lumen Complete ... bowel-movements (suggests complete ... light-switch pain") with complete ... percussion • Nausea ... obstruction #sbo #ileus #pathophysiology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... immunofluorescence Immune Complex ... Post-strep GN, Lupus
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
Causes of Acute ... antibodies • Immune-complex ... IgA, post-strep, lupus ... legionella) • Immune (lupus ... Diagnosis #Algorithm #Causes
How do you work up an ischemic CVA?
A) Initial Evaluation
 • ABCs
 • IV access, monitor
How do you work ... Physical exam (complete ... neuro, NIHSS) ... Evaluate underlying cause ... #CVA #stroke #workup
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
vascular event -> Complete ... > Often mimics complete ... Brown-Sequard Syndrome -> Complete ... and lower motor neuron ... Syndromes #diagnosis #pathophysiology
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Subacute cutaneous lupus ... hair follicles -> causes ... inflammation (complex ... Manifestations #pathophysiology