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diagnosis differential signs vasculitis complications immunology management nephrology rheumatology sle acute agammaglobulinemia aki allergy barre bowel chloride classification dermatology disease
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... Manifestations • Immune Complex ... Myopathy (Also caused ... Complications #pathophysiology ... #signs #symptoms
Mechanical Bowel Obstruction and Ileus - Pathogenesis and Clinical Findings Ileus: Functional bowel "blockage", no peristalsis Mechanical Obstruction:
of bowel lumen Complete ... pain and related symptoms ... bowel-movements (suggests complete ... light-switch pain") with complete ... obstruction #sbo #ileus #pathophysiology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... immunofluorescence Immune Complex ... Post-strep GN, Lupus ... differential #diagnosis #algorithm
Type III Hypersensitivity: Pathogenesis and clinical findings Definition: Small antigen-antibody complexes (produced from normal immune response to
antigen-antibody complexes ... self-antigens are the cause ... : • Systemic Lupus ... antigens are the cause ... Allergy #Immunology #pathophysiology
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm Acute Kidney Injury (AKI) - Acute increase
Causes of Acute ... Differential Diagnosis Algorithm ... antibodies • Immune-complex ... IgA, post-strep, lupus ... legionella) • Immune (lupus
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... hair follicles -> causes ... inflammation (complex ... Manifestations #pathophysiology ... diagnosis #signs #symptoms
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
Causes of Hematuria ... Differential Diagnosis Algorithm ... • Immune-complex ... IgA, post-strep, lupus ... glomerulonephritis • Lupus
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Differential Diagnosis Algorithm ... Autoimmune Vasculitis (lupus ... Work Up: • Complete ... #Causes #dermatology
Pott's Disease in Tuberculosis - Diagnosis and Management Summary Epidemiology: - Typically from TB endemic areas -
extrapulmonary cases ... Clinical Signs/Symptoms ... back pain - Symptoms ... decreased reflexes Pathophysiology ... Mycobacterium tuberculosis complex
Hypochloremia - Differential Diagnosis Algorithm Cause - Decreased Intake: • Low salt in diet • Exclusive D5W
Differential Diagnosis Algorithm ... Cause - Decreased ... homeostasis is complex ... Differential #Diagnosis #Algorithm ... #Pathophysiology
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