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diagnosis oncology differential algorithm leukemia management chronic classification dermatomyositis disorders hodgkins lymphocytic lymphoma antimda5dm antinxp2 antinxp2dm blood causes common comparison
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Phosphorus CLL ... ) CLL Symptoms: ... • Lymphadenopathy ... mosquito bites CLL ... #Leukemia #Hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
• Lymphoid (ALL ... ) - PAS, TdT Lymphadenopathy ... CD10 - T-cell ... • Lymphoid (CLL ... Blood #Disorders #hematology
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm Cervical: - Anterior • Infection
Causes of Localized Lymphadenopathy ... Cervical: - Anterior ... Localized #Focal #Lymphadenopathy ... Algorithm #Causes #Hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
early symptoms • Lymphadenopathy ... Exam/Signs: • Lymphadenopathy ... antigen • Matute’s CLL ... between classical CLL ... workup #oncology #hematology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
the face, or the anterior ... CD4+ and CD8+ T cell ... #AntiMDA5 #Dermatomyositis ... #rheumatology # ... dermatology #diagnosis
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
typically of B-cell ... type (B cell, T ... disease: B symptoms, lymphadenopathy ... Lymphomas • Other hematologic ... #differential #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Lymphocytic Leukemia (CLL ... ) Asymptomatic lymphadenopathy ... Symptomatic massive lymphadenopathy ... uw_IMresidency #CLL ... Leukemia #oncology #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Clinical Features: Fever, Splenomegaly, Hepatomegaly, Lymphadenopathy, Confusion Classic lab findings in HLH: ↑↑ ferritin, Anemia,
Hepatomegaly, Lymphadenopathy ... d-dimer, ↓ NK cell ... (affecting 2 2 cell ... Lymphohistiocytosis #diagnosis #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
(NHL) ~60% - lymphadenopathy ... common - T Cell ... ~10% - B-Cell ... pathophysiology #Hematology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
Summary Framework Hematologic ... sub-types based on the hematologic ... hyperviscosity, lymphadenopathy ... to the plasma cell ... #Significance #hematology
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