11 results
Causes of Diffuse and Localized Lymphadenopathy - Differential Diagnosis Algorithm
 • Reactive (Inflammatory / Infectious)
 •
and Localized Lymphadenopathy ... • Neoplastic (Leukemia ... Focal #Localized #Lymphadenopathy ... Algorithm #Causes #Hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Causes of Diffuse Lymphadenopathy ... Neoplastic: - Leukemia ... Lymphoblastic Leukemia ... Lymphoma #Diffuse #Lymphadenopathy ... Algorithm #Causes #Hematology
Approach to Leukocytosis - Differential Diagnosis Algorithm

Features of hematologic malignancy:
 • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Features of hematologic ... immunosuppression • Exam: lymphadenopathy ... Diagnosis #Algorithm #hematology ... #WBC #Leukemoid
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
pain • Bulky lymphadenopathy ... & BM • Bulky lymphadenopathy ... infections, and lymphadenopathy ... bath/showers • Lymphadenopathy ... #Hematology #Oncology
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm
Cervical:
 - Anterior
     • Infection
Causes of Localized Lymphadenopathy ... Cervical: - Anterior ... Localized #Focal #Lymphadenopathy ... Algorithm #Causes #Hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic Leukemia ... • Most common leukemia ... early symptoms • Lymphadenopathy ... Exam/Signs: • Lymphadenopathy ... workup #oncology #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Chronic Lymphocytic Leukemia ... • Most common leukemia ... ) Asymptomatic lymphadenopathy ... Symptomatic massive lymphadenopathy ... #oncology #hematology
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
the face, or the anterior ... Mechanic's hands #AntiMDA5DM ... #AntiMDA5 #Dermatomyositis ... #rheumatology # ... dermatology #diagnosis
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
(NHL) ~60% - lymphadenopathy ... Treated Like Acute Leukemias ... pathophysiology #Hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
involved) • No leukemic ... disease: B symptoms, lymphadenopathy ... Lymphomas • Other hematologic ... #differential #hematology