33 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... transformation to acute ... agents to improve counts ... Management #treatment #hematology ... #oncology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Elevated Platelet Count ... → Refer to hematology ... • Nonmalignant hematologic ... Kawasaki, Nephrotic syndrome ... Diagnosis #Algorithm #hematology
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
Diagnosis Framework HEMATOLOGIC ... Hyperviscosity Syndrome ... Absolute neutrophil count ... : Tumor Lysis Syndrome ... Hyperuricemia • Acute
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Causes of Diffuse ... Fatigue • Acute ... Diagnosis #Algorithm #Causes ... #Hematology #Oncology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Kasabach-Merritt syndrome ... - APLS • Acute ... Gardner-Diamond syndrome ... Differential #Diagnosis #hematology ... #nonpalpable #dermatology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Causes of Thrombocytosis ... Thrombocytosis): • Acute ... Myelodysplastic syndrome ... Differential #Diagnosis #Causes ... #hematology #secondary
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
white blood cell count ... translocation • Acute ... thrombocythemia • Acute ... Chickenpox Other Causes ... #hematology #basophils
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
Decreased CD4 ... counts and a raised ... CD4+/CD8+ ratio ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... and petechiae Causes ... from low blood counts ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Acute Retroviral Syndrome
Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection

 •
Syndrome Acute ... during transient CD4 ... + T-cell count can ... Leukocyte-lymphocyte subset counts ... progression by slowing CD4