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diagnosis differential leukemia management mds myelodysplastic anemia chronic cll dermatology idiopathic lymphocytic lymphocytopenia lymphopenia myelodysplasia platelets syndromes thrombocytosis treatment workup
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
dys- (abnormal) -plastic ... transformation to acute ... agents to improve counts ... Management #treatment #hematology ... #oncology
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia DIAGNOSTIC CRITERIA FOR ICL • Persistent CD4 T-cell lymphopenia •
T-cell count of ... chemotherapy) • Genetic syndromes ... Heme (lymphoma. aplasia ... #diagnosis #hematology ... #Differential #Causes
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... and petechiae Causes ... from low blood counts ... #Anemia #oncology ... #hematology #diagnosis
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Elevated Platelet Count ... → Refer to hematology ... Kawasaki, Nephrotic syndrome ... Glucocorticoids, IL ... #hematology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Sweet Syndrome ... Acute febrile ... Causes: - Idiopathic ... Sweet syndrome ... #dermatology #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... Out Secondary Causes ... • Anemia • Aplastic ... #diagnosis #hematology ... #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
surface molecules: CD5 ... Pure red cell aplasia ... ’s lymphoma or acute ... diagnosis #workup #oncology ... #hematology
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