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differential hematology management erythematosus lupus systemic treatment acquired activation algorithm antibodies associations autoimmune causes cerebritis classification cns conditions cryoglobulinemia cryoglobulins
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Autoantibodies and ... - Vasculitis, e.g ... - Vasculitis, e.g ... Associations #diseases #diagnosis ... #table #rheumatology
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... - Diagnosis and ... Management • Autoantibodies ... Lymphoproliferative disorders (e.g ... Myeloproliferative disorders (e.g
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Toxic Damage (e.g ... Displacement (e.g ... Autoimmune • ITP • SLE ... Non-lmmune: • HELLP Syndrome ... Foreign Surface (e.g
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Demyelinating Syndrome ... the formation of autoantibodies ... Lumbar Puncture, EEG ... CNS #neurology #rheumatology
Raynaud Phenomenon Differential Diagnosis: Rheumatologic - MCC systemic sclerosis, RA, SLE, Sjogren syndrome, Antisynthetase syndrome, MCTD Heme -
Phenomenon Differential Diagnosis ... : Rheumatologic ... sclerosis, RA, SLE ... Hypercoagulable state (eg ... Chemotherapy (eg
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
GI - Felty syndrome ... disease, Vasculitis (e.g ... , Behçet's syndrome ... #differential #diagnosis ... #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
• Anti-Ro/SSA autoantibodies ... Differential Diagnosis ... • Malignancy (e.g ... Endocrine disorders (e.g ... #Rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
underlying disease (eg ... erythematosus [SLE ... • Infection (eg ... #Diagnosis #Management ... #Hematology #Rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
diseases: - 10% SLE ... Labs/Diagnosis: ... tissue disorder (e.g ... erythematosus (SLE ... classification #rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential Diagnosis ... Aldolase levels • EMG ... RP-ILD), dermato-rheumatologic ... Mechanic's hands Autoantibodies ... Myositis #Myopathy #rheumatology
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