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diagnosis ana rheumatology antibody abnormal alopecia antibodies causes cytoplasmic dermatology disorders hairloss hepatology lfts nuclear aggregometry classification cystic dcld disease
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
Antinuclear Antibody ... Testing - Nuclear ... and Cytoplasmic Patterns ... Nuclear Patterns ... #differential #
Antinuclear Antibody Testing - Nuclear Patterns Homogeneous pattern: • SLE, SSc, AIH, JIA • dsDNA, chromatin,
Testing - Nuclear ... Patterns Homogeneous ... pattern: • SLE ... cases) Speckled pattern ... #differential #
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... • Nucleolar: Diffuse ... Kumfer @AnnKumfer #Antinuclear ... Antibodies #ANA #patterns ... diagnosis #differential
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
serial dilution, a pattern ... significant • Pattern ... : The ANA patterns ... not specific ANA Patterns ... Antibodies #ANA #patterns
Antinuclear Antibody Testing Cytoplasmic Patterns Reticular/AMA: • PBC, SSc, PBC/SSc OS, PBC/SjS OS • AMA Speckled: •
Antinuclear Antibody ... Patterns Reticular ... : • SLE, SjS, CTD-ILD ... #Cytoplasmic #Patterns ... #differential #
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Function Tests - Differential ... Diagnosis Algorithm ... Hepatocellular Pattern ... dz Cholestatic Pattern ... Ducts - CBD
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm DIFFUSE Scarring - Irreversible-biopsy required • Lupus
and Focal) Differential ... Diagnosis Algorithm ... planopilaris Pattern ... #Differential # ... Diagnosis #Algorithm
Platelet disorders and Aggregometry Glanzmann Thrombasthenia • Defective aggregation to all agonists except ristocetin • Normal platelet,
similar aggregation pattern ... agonists • This pattern ... aggregation to HD ... considered first-line testing ... Platelet #disorders #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Diagnosis Algorithm ... lymphadenopathy more diffuse ... involvement, irregular pattern ... pathophysiology #Hematology ... #algorithm
Diffuse Hair Loss (Alopecia) - Differential Diagnosis Algorithm Scarring - Irreversible-biopsy required • Lupus erythematosus • Lichen
Diffuse Hair Loss ... (Alopecia) - Differential ... Diagnosis Algorithm ... planopilaris Pattern ... #Differential #
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