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diagnosis dress reactions syndrome blood product rheumatology transfusion adultonset agep apml compared differentiation disease diseases drug emergency eosinophilia eosinophilic erythemas
DRESS Syndrome vs SJS/TEN DRESS • Latency: 2-8 weeks • Rash: Morbilliform • Mucosal involvement: 50% have
: 2-8 weeks • Rash ... : 4-28 days • Rash ... Prerenal azotemia • Skin ... Syndrome #SJS #TEN #comparison ... #table #dermatology
Severe Drug Rashes - Comparison - DRESS | SJS/TEN | AGEP | Erythroderma DRESS - Onset:
Drug Rashes - Comparison ... >90% of total skin ... #TABLE #DRESS # ... #Erythroderma #Dermatology ... #Emergency #Differential
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Arthralgia/arthritis, Skin ... rash ± odynophagia ... fraction < 20% Differential ... hepatitis • Pulmonary ... Disease #diagnosis #management
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
: Age>60, CKD, CHF ... , and CXR with pulmonary ... Transfusion #Reactions #hematology ... #diagnosis #comparison ... #table
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
characterized by extensive skin ... rash in association ... Skin involvement ... Resolution > 15 days Differentials ... DRESS #Syndrome #dermatology
Approach to Eosinophilic Lung Diseases • Acute Eosinophilic Pneumonia (< 1 wk) - ~30yo, M; Recent
loss; CV, CNS, skin ... Lung #Diseases #pulmonary ... #differential # ... diagnosis #comparison ... #table #eosinophilia
Erythemas Summarized Erythema ab igne • A dermatosis that results from repeated exposure to heat (fires, heating
centrifugum • A chronic skin ... gyratum repens • A skin ... PrathitKulkarni #Erythemas #comparison ... #table #differential ... #diagnosis #dermatology
Scleroderma Like Conditions - Differential Diagnosis Eosinophilic Fasciitis: - Orange peel induration (peau d'orange) of proximal extremities
Like Conditions - Differential ... eosinophilia, skin ... #Scleroderma #Differential ... #Diagnosis #comparison ... #table #dermatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Imaging: CXR- pulmonary ... initiation • Differential ... sepsis), PE, DAH, CHF ... APML #diagnosis #management ... #hematology #oncology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Vasculitis Differential ... , mucositis • Rash ... Cerebrospinal fluid (CSF ... #Diagnosis #Rheumatology
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