54 results
diagnosis differential algorithm causes oncology workup liver management table appearance hemolytic lesions pancytopenia radiology thrombocytosis treatment platelets pocus rheumatology thrombocytopenia
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias ... Algorithm Signs of anemia ... Reticulocytes • Abnormal peripheral ... #Hemolytic #Anemias ... Diagnosis #Algorithm #hematology
Laboratory Testing in Hemolytic Anemia Intravascular vs Extravascular Hemolysis Reticulocytes Unconjugated bilirubin LDH Peripheral smear Haptoglobin Urine hemosiderin Urine hemoglobin Carboxyhemoglobin #Hemolytic #Anemia #Laboratory #Testing #workup
Testing in Hemolytic Anemia ... bilirubin LDH Peripheral ... #Hemolytic #Anemia ... workup #diagnosis #hematology
Peripheral Blood Smear Analysis Hypochromia Megaloblastic Anemia Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS) Microspherocytes: Autoimmune hemolytic anemia Sickled red
Peripheral Blood ... Megaloblastic Anemia ... Autoimmune hemolytic anemia ... EricsMedicalLectures/ #Peripheral ... Smear #Analysis #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Chronic Myelogenous Leukemia ... Non malignant hematologic ... states • Non-hematologic ... Iron deficiency anemia ... Algorithm #Causes #Hematology
Approach to Leukocytosis - Differential Diagnosis Algorithm Features of hematologic malignancy: • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Features of hematologic ... hepatomegaly • Labs: anemia ... Diagnosis #Algorithm #hematology ... #WBC #Leukemoid
Thrombocytosis - Differential Diagnosis Platelet Count > 450 Reactive: • Anemia/blood loss (Fe deficiency) • Infection/Sepsis • Non-infectious
Reactive: • Anemia ... Chronic Myeloid Leukemia ... causes #Platelets #hematology
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
Medications - Heparin ... • Acute DIC - Septic ... promyelocytic leukemia ... Summary #table #comparison ... #diagnosis #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
blasts in the peripheral ... maturation • (Peripheral ... - infiltrates (anemia ... • ↓Hg & PLT • Peripheral ... #Hematology #Oncology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... • Symptomatic anemia ... megaloblastic anemia ... to MDS or acute leukemia ... management #treatment #hematology
Peripheral blood findings in microangiopathic hemolytic anemia. DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... microangiopathic hemolytic anemia ... Microangiopathic hemolytic anemia ... (black arrow) Peripheral ... #Hematology #Pathology
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